SCHEMBL29913652

SCHEMBL29913652

NS(=O)(=O)c1cc(C(F)(F)F)ccc1C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA9 Q16790 2/20 0.55
CA12 O43570 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA14 Q9ULX7 1/20 0.55
CA5B Q9Y2D0 1/20 0.55
KIF11 P52732 5/20 0.47
CES2 O00748 2/20 0.47
ALOX5AP P20292 2/20 0.45
FEN1 P39748 2/20 0.45
PTGES2 Q9H7Z7 2/20 0.43
LMNA P02545 2/20 0.41
AR P10275 1/20 0.41
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18985068 1.00 CA1 (0.55) CA1CA2CA9CA12CA4
SCHEMBL9048102 0.85 CA1 (0.55) CA1CA2CA9CA12CA4
SCHEMBL30161533 0.81 TRPV4 (0.47) CES2LMNAKMT2AALDH1A1MEN1
SCHEMBL941069 0.81 TRPV4 (0.47) CES2LMNAKMT2AALDH1A1MEN1
SCHEMBL3190051 0.81 CES2 (0.52) CA1CA2CES2KMT2AALDH1A1
SCHEMBL23841300 0.81 CES2 (0.47) KIF11CES2ALOX5APFEN1KMT2A
SCHEMBL31296460 0.81 CA12 (0.55) CA1CA2CA9CA12CA4
SCHEMBL2777161 0.81 ALOX5AP (0.51) CA1CA2CA9CA12CA4
SCHEMBL30543023 0.81 ALOX5AP (0.51) CA1CA2CA9CA12CA4
SCHEMBL2182720 0.81 KIF11 (0.47) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN claimed
CN-119219809-A Fluorine-containing polymer, preparation method thereof and ion exchange membrane 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
CN-115044224-B High-alkali-resistance and vividness disperse dye and preparation method and application thereof 南通大学 2023-07-18 CN disclosed
CN-115044224-A High-alkali-resistance and high-brilliance-degree disperse dye and preparation method and application thereof 南通大学 2022-09-13 CN disclosed