Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | METAP2 | P50579 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13823613 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL1466906 | 0.85 | ALDH1A1 (0.72) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL15822907 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL16127963 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL23200377 | 0.81 | METAP2 (0.76) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL3279765 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL23879580 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL1688339 | 0.81 | METAP2 (0.71) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL12200779 | 0.81 | CCR2 (0.73) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL27770303 | 0.81 | KDM4E (0.68) | ALDH1A1KDM4EKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101519368-A | Small molecule entry inhibitors | TIBOTEC PHARM LTD (IE) | 2009-09-02 | — | — | CN | claimed |