Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | DHPS | P49366 | 12/20 | 0.37 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397108 | 0.87 | SLC10A2 (0.40) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1397142 | 0.84 | KMO (0.44) | KMODHPSNEK2KDM4EALDH1A1 | |
| SCHEMBL1397030 | 0.79 | DHPS (0.54) | KMODHPSNEK2KDM4EALDH1A1 | |
| SCHEMBL1397033 | 0.78 | DHPS (0.36) | KMODHPSKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1918257 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1 | |
| SCHEMBL20727090 | 0.76 | POLB (0.41) | DHPSKDM4E | |
| SCHEMBL20727040 | 0.76 | KMO (0.43) | KMODHPSNEK2AKR1C3AKR1C2 | |
| SCHEMBL16036648 | 0.75 | NEK2 (0.40) | DHPSNEK2HSD17B10 | |
| SCHEMBL16035711 | 0.75 | NEK2 (0.40) | DHPSNEK2 | |
| SCHEMBL29556583 | 0.75 | NEK2 (0.40) | DHPSNEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784531-B | 2- (substituted phenyl) -6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylic acid derivatives and their use as herbicides | DOW AGROSCIENCES LLC | 2013-05-01 | — | — | CN | claimed |
| CN-103254137-A | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and use thereof as herbicides | DOW AGROSCIENCES LLC | 2013-08-21 | — | — | CN | disclosed |
| CN-101784531-B | 2- (substituted phenyl) -6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylic acid derivatives and their use as herbicides | DOW AGROSCIENCES LLC | 2013-05-01 | — | — | CN | disclosed |
| CN-101784531-A | 2- (substituted phenyl) -6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylic acid derivatives and their use as herbicides | DOW AGROSCIENCES LLC | 2010-07-21 | — | — | CN | disclosed |