Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857605 | 0.86 | ACHE (0.58) | HTR7GAAACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL14850872 | 0.85 | AKR1C3 (0.55) | HTR7GAAACHEAPPCA12 | |
| SCHEMBL3958057 | 0.85 | ACHE (0.52) | HTR7GAAACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL5184745 | 0.84 | ACHE (0.56) | HTR7GAAACHEAPPCA12 | |
| SCHEMBL11281941 | 0.83 | HTR7 (0.58) | HTR7APPCA12CA1CA2 | |
| SCHEMBL10094682 | 0.83 | HTR7 (0.58) | HTR7APPCA12CA1CA2 | |
| SCHEMBL18083450 | 0.81 | ACHE (0.44) | HTR7GAAACHEAPPCA12 | |
| SCHEMBL321430 | 0.81 | CA1 (0.55) | HTR7APPCA12CA1CA2 | |
| SCHEMBL13069497 | 0.81 | ACHE (0.52) | HTR7GAAACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL277877 | 0.80 | S1PR1 (0.48) | HTR7ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013152-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2011-09-06 | — | — | US | claimed |
| US-20100197667-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2010-08-05 | — | — | US | claimed |
| US-7728144-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC (US) | 2010-06-01 | — | — | US | claimed |
| EP-1893577-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2006138218-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-12-28 | — | — | WO | claimed |
| US-20060281740-A1 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE BIOPHARMA R&D IP, LLC | 2006-12-14 | — | — | US | claimed |
| EP-0187520-B1 | WATER-SOLUBLE DYE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-24 | — | — | EP | claimed |
| US-4777248-A | Water-soluble non-reactive triazinyl mono-azo dye for ink jet printing | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-11 | — | — | US | claimed |
| EP-0187520-A2 | Water-soluble dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-16 | — | — | EP | claimed |
| US-11912916-B2 | Organic electroluminescent compound and organic electroluminescent device comprising the same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2024-02-27 | — | — | US | disclosed |
| US-11247969-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2022-02-15 | — | — | US | disclosed |
| US-20210363419-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2021-11-25 | — | — | US | disclosed |
| US-20210024493-A1 | Diamide Compounds Having Muscarinic Receptor Antagonist and Beta2 Adrenergic Receptor Agonist Activity | THERAVANCE RESPIRATORY COMPANY, LLC | 2021-01-28 | — | — | US | disclosed |
| US-10836744-B2 | Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity | THERAVANCE RESPIRATORY COMPANY, LLC (US) | 2020-11-17 | — | — | US | disclosed |
| WO-1995017471-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-06-29 | — | — | WO | disclosed |
| WO-1995017472-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-06-29 | — | — | WO | disclosed |
| EP-0187520-B1 | WATER-SOLUBLE DYE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-24 | — | — | EP | disclosed |
| US-4777248-A | Water-soluble non-reactive triazinyl mono-azo dye for ink jet printing | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-11 | — | — | US | disclosed |
| US-4726844-A | LIGHTFASTNESS | CANON KABUSHIKI KAISHA (JP) | 1988-02-23 | — | — | US | disclosed |
| EP-0187520-A2 | Water-soluble dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836744-B2 | Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity | ADRB2, ADRB1, ADRA2A | HTR7 319/4885GAA 3449/4885ACHE 306/4885 |
| US-11247969-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | CHRM2, CHRM1, CHRM3 | HTR7 270/4885GAA 4761/4885ACHE 604/4885 |
| US-20100197667-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | CHRM2, CHRM3, CHRM5 | HTR7 164/4885GAA 4481/4885ACHE 344/4885 |
| US-20210024493-A1 | Diamide Compounds Having Muscarinic Receptor Antagonist and Beta2 Adrenergic Receptor Agonist Activity | ADRB2, ADRB1, ADRA2B | HTR7 606/4885GAA 2954/4885ACHE 477/4885 |
| US-20060281740-A1 | Biphenyl compounds useful as muscarinic receptor antagonists | CHRM2, CHRM3, CHRM5 | HTR7 164/4885GAA 4481/4885ACHE 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.