Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 16/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776334 | 0.84 | HMOX1 (0.53) | HMOX1CCR1ABL1BCRKMT2A | |
| Hydrochloric Acid SCHEMBL2775583 | 0.82 | HMOX1 (0.42) | HMOX1CCR1 | |
| SCHEMBL2775185 | 0.82 | CCR1 (0.41) | HMOX1CCR1KMT2AKCNH2 | |
| SCHEMBL6526701 | 0.79 | HMOX1 (0.40) | HMOX1CCR1 | |
| SCHEMBL2775086 | 0.75 | GPR119 (0.42) | HMOX1 | |
| SCHEMBL2777053 | 0.74 | CCR1 (0.48) | CCR1KCNH2 | |
| SCHEMBL2778165 | 0.74 | CCR1 (0.48) | HMOX1CCR1KMT2AKCNH2 | |
| SCHEMBL2779821 | 0.72 | CCR1 (0.47) | HMOX1CCR1KMT2AKCNH2 | |
| SCHEMBL2776929 | 0.72 | LMNA (0.48) | HMOX1CCR1KMT2AKCNH2 | |
| SCHEMBL2776253 | 0.71 | LIPE (0.45) | HMOX1CCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |