Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677176 | 1.00 | SLC6A9 (0.45) | SLC6A9HSD17B10ALBPOLBMAPK1 | |
| SCHEMBL15780321 | 1.00 | SLC6A9 (0.45) | SLC6A9HSD17B10ALBPOLBMAPK1 | |
| SCHEMBL25137537 | 0.92 | SLC6A9 (0.40) | SLC6A9HSD17B10ALBPOLBMAPK1 | |
| SCHEMBL16922658 | 0.92 | MAPT (0.44) | SLC6A9HSD17B10TACR1MAPTALDH1A1 | |
| SCHEMBL17190336 | 0.92 | MAPT (0.44) | SLC6A9HSD17B10TACR1MAPTALDH1A1 | |
| SCHEMBL15444498 | 0.89 | SLC6A9 (0.38) | SLC6A9HSD17B10ALBPOLBMAPK1 | |
| SCHEMBL12768265 | 0.89 | CHRM5 (0.40) | SLC6A9HSD17B10ALBPOLBMAPK1 | |
| SCHEMBL8562008 | 0.88 | HSD17B10 (0.43) | HSD17B10POLBMAPK1L3MBTL1MAPT | |
| SCHEMBL11713448 | 0.88 | HSD17B10 (0.43) | HSD17B10POLBMAPK1L3MBTL1MAPT | |
| SCHEMBL17706711 | 0.88 | HSD17B10 (0.43) | HSD17B10POLBMAPK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8444954-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-05-21 | — | — | US | disclosed |
| US-8420053-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| US-8420050-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| US-8414864-B2 | Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2013-04-09 | — | — | US | disclosed |
| US-7850947-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2010-12-14 | — | — | US | disclosed |
| WO-2009143101-A2 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2009-11-26 | — | — | WO | disclosed |
| US-7611692-B2 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2009-11-03 | — | — | US | disclosed |
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2009-07-09 | — | — | US | disclosed |
| EP-1706154-A4 | IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO SPA (IT) | 2008-11-26 | — | — | EP | disclosed |
| US-20080247946-A1 | Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2008-10-09 | — | — | US | disclosed |
| US-20070231257-A1 | Radiodiagnosis, radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2007-10-04 | — | — | US | disclosed |
| US-7226577-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING, S. P. A. (IT) | 2007-06-05 | — | — | US | disclosed |
| US-20060239914-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-10-26 | — | — | US | disclosed |
| US-20060241018-A1 | Linkers for radiopharmaceutical compounds | BRACCO IMAGING S.P.A. (IT) | 2006-10-26 | — | — | US | disclosed |
| US-20060239923-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-10-26 | — | — | US | disclosed |
| EP-1706154-A1 | IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS | Bracco Imaging, S.P.A. (IT) | 2006-10-04 | — | — | EP | disclosed |
| US-20060018830-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-01-26 | — | — | US | disclosed |
| WO-2005067983-A1 | IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2005-07-28 | — | — | WO | disclosed |
| US-20040253225-A1 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2004-12-16 | — | — | US | disclosed |
| US-20040136906-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060239914-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | SLC6A9 1552/4885HSD17B10 4843/4885ALB 619/4885 |
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | SLC6A9 927/4885HSD17B10 4647/4885ALB 924/4885 |
| US-20040253225-A1 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | GRPR, MLNR, NPBWR1 | SLC6A9 2587/4885HSD17B10 4878/4885ALB 3350/4885 |
| US-20060239923-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | SLC6A9 2279/4885HSD17B10 4866/4885ALB 2265/4885 |
| US-20060018830-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | SLC6A9 1552/4885HSD17B10 4843/4885ALB 619/4885 |
| US-20060241018-A1 | Linkers for radiopharmaceutical compounds | VIP, QPCT, NPPA | SLC6A9 4458/4885HSD17B10 4852/4885ALB 1814/4885 |
| US-20070231257-A1 | Radiodiagnosis, radiotherapy | GRPR, MRGPRX2, MRGPRX1 | SLC6A9 1275/4885HSD17B10 4783/4885ALB 2544/4885 |
| US-20040136906-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, MLNR | SLC6A9 2144/4885HSD17B10 4863/4885ALB 2192/4885 |
| US-20080247946-A1 | Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy | GRPR, MRGPRX1, BRS3 | SLC6A9 2291/4885HSD17B10 4880/4885ALB 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.