SCHEMBL992344

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL991535	0.88	TDP1 (0.55)	KMT2ATDP1MEN1CASP6POLB
	SCHEMBL12950492	0.84	THRB (0.44)	KMT2ATDP1ALDH1A1TSHRTHRB
	SCHEMBL992135	0.83	POLB (0.61)	KMT2ATDP1MEN1ALDH1A1KDM4E
	SCHEMBL1079065	0.81	ALDH1A1 (0.57)	KMT2ATDP1MEN1ALDH1A1TSHR
	SCHEMBL11980693	0.81	TDP1 (0.57)	KMT2ATDP1ALDH1A1TSHRTHRB
	SCHEMBL19442012	0.80	KDM4E (0.50)	KMT2ATDP1ALDH1A1TSHRTHRB
	SCHEMBL991053	0.78	KMT2A (0.51)	KMT2ATDP1MEN1ALDH1A1
	SCHEMBL992517	0.77	LMNA (0.54)	KMT2ATDP1MEN1ALDH1A1TSHR
	SCHEMBL991587	0.76	ALDH1A1 (0.52)	KMT2ATDP1MEN1ALDH1A1TSHR
	SCHEMBL14857328	0.75	KDM4E (0.41)	KMT2AALDH1A1TSHRTHRBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.