SCHEMBL27866539

SCHEMBL27866539

Cn1cnc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PAX8 Q06710 1/20 0.54
▸ LMNA P02545 2/20 0.53
▸ TP53 P04637 2/20 0.53
▸ GMNN O75496 1/20 0.53
▸ ALDH1A1 P00352 1/20 0.53
▸ NFKB1 P19838 1/20 0.53
▸ DNMT1 P26358 1/20 0.53
▸ THPO P40225 1/20 0.53
▸ MTOR P42345 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ RAB9A P51151 1/20 0.53
▸ BLM P54132 1/20 0.53
▸ HBB P68871 1/20 0.53
▸ PMP22 Q01453 1/20 0.53
▸ HPGD P15428 1/20 0.52
▸ DPP4 P27487 1/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ SLC28A1 O00337 1/20 0.51
▸ MAP3K7 O43318 1/20 0.51
▸ SLC28A2 O43868 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685844 0.88 MEN1 (0.49) PAX8LMNATP53GMNNALDH1A1
SCHEMBL20267951 0.86 ADORA3 (0.52) LMNATP53DPP4MEN1SLC28A1
SCHEMBL31685368 0.85 ADORA1 (0.53) ADORA1SMN1; SMN2
SCHEMBL31685447 0.84 DNPH1 (0.59) ADORA1SMN1; SMN2
SCHEMBL873210 0.84 LMNA (0.58) LMNATP53GMNNALDH1A1NFKB1
SCHEMBL1979500 0.84 LMNA (0.58) LMNATP53GMNNALDH1A1NFKB1
SCHEMBL30443215 0.82 PAX8 (0.51) PAX8LMNATP53GMNNALDH1A1
SCHEMBL19359092 0.81 TYMP (0.65) PAX8LMNATP53HPGDDPP4
SCHEMBL18512995 0.81 TYMP (0.65) PAX8LMNATP53HPGDDPP4
SCHEMBL23414481 0.80 LMNA (0.59) PAX8LMNATP53GMNNALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed
CN-120158444-A Negative selection method and system for purifying circular nucleic acid 上海环码生物医药有限公司 2025-06-17 — — CN disclosed
CN-120082543-A Negative selection method and system for purifying circular nucleic acid 上海环码生物医药有限公司 2025-06-03 — — CN disclosed
CN-117866948-B Negative selection method and system for purifying circular nucleic acid 上海环码生物医药有限公司 2024-12-13 — — CN disclosed
WO-2023056980-A1 DESIGN OF SELF-REPLICATING RNA MOLECULES AND APPLICATION THEREOF 吴可行 2023-04-13 — — WO disclosed
CN-107849574-B UTR for increasing translation efficiency of RNA molecules 埃泽瑞斯公司 2021-11-05 — — CN disclosed
CN-104056668-A Explosive liquid package and use thereof UNIV NORTHWESTERN 2014-09-24 — — CN disclosed
CN-102387966-A Explosive liquid package and use thereof UNIV NORTHWESTERN 2012-03-21 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 PAX8 1885/4885LMNA 240/4885TP53 557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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