Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 8/20 | 0.39 |
| ▸ | MMP3 | P08254 | 5/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883822 | 0.90 | OPRD1 (0.43) | OPRD1OPRM1OPRK1AGTR2MMP8 | |
| SCHEMBL27867498 | 0.88 | AGTR2 (0.51) | OPRD1OPRM1OPRK1AGTR2MMP8 | |
| SCHEMBL27867426 | 0.88 | NOTUM (0.42) | AGTR2 | |
| SCHEMBL27867411 | 0.86 | MMP8 (0.42) | AGTR2MMP8MMP3 | |
| SCHEMBL27883807 | 0.85 | AADAT (0.43) | AGTR2MMP8MMP3 | |
| SCHEMBL27867499 | 0.80 | AGTR2 (0.38) | AGTR2FPR2 | |
| SCHEMBL27883817 | 0.80 | FFAR1 (0.47) | AGTR2MMP8MMP3 | |
| SCHEMBL27883804 | 0.80 | KMO (0.46) | AGTR2 | |
| SCHEMBL27867409 | 0.78 | AGTR2 (0.52) | OPRD1OPRM1OPRK1AGTR2 | |
| SCHEMBL27883815 | 0.75 | MMP8 (0.43) | AGTR2MMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | claimed |
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | disclosed |