Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 11/20 | 0.42 |
| ▸ | MMP3 | P08254 | 7/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ALAD | P13716 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883815 | 0.90 | MMP8 (0.43) | MMP8MMP3MMP13HSD17B3AGTR2 | |
| SCHEMBL27867498 | 0.88 | AGTR2 (0.51) | MMP8MMP3HSD17B3AGTR2 | |
| SCHEMBL27867447 | 0.86 | OPRD1 (0.43) | MMP8MMP3AGTR2 | |
| SCHEMBL27883870 | 0.82 | AADAT (0.46) | MMP8MMP3AADATTDP1L3MBTL1 | |
| SCHEMBL27883807 | 0.82 | AADAT (0.43) | MMP8MMP3AGTR2AADAT | |
| SCHEMBL27883817 | 0.80 | FFAR1 (0.47) | MMP8MMP3MMP13AGTR2 | |
| SCHEMBL27883804 | 0.80 | KMO (0.46) | AGTR2 | |
| SCHEMBL27867409 | 0.78 | AGTR2 (0.52) | HSD17B3AGTR2 | |
| SCHEMBL27867426 | 0.76 | NOTUM (0.42) | AGTR2 | |
| SCHEMBL27883816 | 0.75 | TDP2 (0.43) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | claimed |
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | disclosed |