Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 5/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792001 | 0.92 | TRPV3 (0.33) | CACNA1GTRPV3 | |
| SCHEMBL2790130 | 0.85 | ALOX5AP (0.34) | TRPV3 | |
| SCHEMBL2841338 | 0.80 | SIRT2 (0.32) | TRPV3 | |
| SCHEMBL2835561 | 0.80 | GFER (0.31) | TRPV3 | |
| SCHEMBL7900706 | 0.79 | ALOX5AP (0.42) | TRPV3 | |
| SCHEMBL2835610 | 0.79 | GFER (0.31) | TRPV3 | |
| SCHEMBL2837000 | 0.78 | ALDH1A1 (0.36) | — | |
| SCHEMBL7905913 | 0.77 | CACNA1B (0.35) | — | |
| SCHEMBL7905963 | 0.75 | PROKR1 (0.35) | — | |
| SCHEMBL2791623 | 0.73 | FPR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |