Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 6/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PPIB | P23284 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792001 | 0.93 | TRPV3 (0.33) | ALOX5APFEN1PROKR1ALDH1A1TSHR | |
| SCHEMBL2841338 | 0.87 | SIRT2 (0.32) | ALOX5APFEN1PROKR1GPR119TRPV3 | |
| SCHEMBL2835561 | 0.87 | GFER (0.31) | GPR119TRPV3GFER | |
| SCHEMBL2835610 | 0.86 | GFER (0.31) | GPR119TRPV3GFER | |
| SCHEMBL2789073 | 0.85 | CACNA1G (0.31) | TRPV3 | |
| SCHEMBL2837000 | 0.85 | ALDH1A1 (0.36) | PROKR1ALDH1A1KMT2AGPR119REN | |
| SCHEMBL7890024 | 0.83 | KLK5 (0.36) | ALOX5APFEN1PROKR1ALDH1A1TSHR | |
| SCHEMBL2813840 | 0.83 | KLK5 (0.36) | ALOX5APFEN1PROKR1ALDH1A1TSHR | |
| SCHEMBL2813838 | 0.83 | KLK5 (0.36) | ALOX5APFEN1PROKR1ALDH1A1TSHR | |
| SCHEMBL7900706 | 0.82 | ALOX5AP (0.42) | ALOX5APFEN1PROKR1GPR119TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |