Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835561 | 0.92 | GFER (0.31) | GFERGPR119TRPV3 | |
| SCHEMBL2841338 | 0.90 | SIRT2 (0.32) | GFERGPR119TRPV3 | |
| SCHEMBL2790130 | 0.86 | ALOX5AP (0.34) | GFERGPR119TRPV3 | |
| SCHEMBL2792001 | 0.86 | TRPV3 (0.33) | GFERGPR119TRPV3 | |
| SCHEMBL2837000 | 0.86 | ALDH1A1 (0.36) | GFERGPR119 | |
| SCHEMBL7900974 | 0.86 | PABPC1 (0.32) | — | |
| SCHEMBL2787942 | 0.84 | DPP4 (0.33) | GFER | |
| SCHEMBL2787940 | 0.84 | DPP4 (0.33) | GFER | |
| SCHEMBL2789073 | 0.79 | CACNA1G (0.31) | TRPV3 | |
| SCHEMBL7897783 | 0.78 | PABPC1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |