Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28022336 | 0.80 | GPR119 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28022342 | 0.75 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28022859 | 0.75 | GAA (0.53) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL14061760 | 0.74 | MEN1 (0.40) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6262157 | 0.74 | MEN1 (0.40) | ALDH1A1MEN1KMT2ATDP1 | |
| Ammonium Lupinoate SCHEMBL4037708 | 0.72 | TDP1 (0.47) | MEN1KMT2ACYP2D6LMNATDP1 | |
| Ammonium Lupinoate SCHEMBL29108993 | 0.71 | TDP1 (0.46) | ALDH1A1MEN1KMT2ATDP1 | |
| Ammonium Lupinoate SCHEMBL27185103 | 0.71 | TDP1 (0.46) | ALDH1A1MEN1KMT2ATDP1 | |
| Ammonium Lupinoate SCHEMBL29108995 | 0.71 | TDP1 (0.46) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL10340120 | 0.69 | TDP1 (0.44) | MEN1KMT2ACYP2D6LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103491955-B | Combination of a phosphatidylinositol-3-kinase (PI3K) inhibitor and an MTOR inhibitor | NOVARTIS AG (CH) | 2015-12-23 | — | — | CN | claimed |
| CN-103491955-A | Combination of a phosphatidylinositol-3-kinase (PI3K) inhibitor and an MTOR inhibitor | NOVARTIS AG | 2014-01-01 | — | — | CN | claimed |
| CN-103491955-B | Combination of a phosphatidylinositol-3-kinase (PI3K) inhibitor and an MTOR inhibitor | NOVARTIS AG (CH) | 2015-12-23 | — | — | CN | disclosed |
| CN-103491955-A | Combination of a phosphatidylinositol-3-kinase (PI3K) inhibitor and an MTOR inhibitor | NOVARTIS AG | 2014-01-01 | — | — | CN | disclosed |