Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | USP14 | P54578 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27921139 | 0.85 | USP14 (0.52) | HDAC6PLA2G2AUSP14KDM4EATM | |
| Bromobenzene SCHEMBL27704781 | 0.80 | ALDH1A1 (0.47) | HDAC6PLA2G2AKDM4EL3MBTL1MAPT | |
| SCHEMBL17906201 | 0.79 | KDM4E (0.44) | HDAC6PLA2G2AUSP14TSHRKDM4E | |
| SCHEMBL27794781 | 0.77 | PLA2G2A (0.51) | HDAC6PLA2G2AKDM4ERORCPTGDR2 | |
| SCHEMBL27704780 | 0.77 | HDAC1 (0.54) | HDAC6PLA2G2AKDM4EPTGDR2MAPT | |
| SCHEMBL27921138 | 0.75 | PLA2G2A (0.49) | HDAC6PLA2G2AUSP14KDM4ERORC | |
| SCHEMBL3969842 | 0.75 | GPR3 (0.56) | TSHRKDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL262160 | 0.74 | KDM4E (0.67) | TSHRKDM4EATML3MBTL1NPC1 | |
| SCHEMBL29400116 | 0.74 | KDM4E (0.67) | TSHRKDM4EATML3MBTL1NPC1 | |
| SCHEMBL18892113 | 0.71 | HDAC6 (0.38) | HDAC6PLA2G2AUSP14TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101360422-B | Oncogenic Ras-specific cytotoxic compound and methods of usethereof | UNIV TEXAS | 2013-10-23 | — | — | CN | claimed |