SCHEMBL3021565

SCHEMBL3021565

C=Cc1cccc(C#N)c1C=C1C(=O)N(C)C(Cc2ccccc2)C(=O)N1C

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.34
RIPK1 Q13546 2/20 0.31
HDAC6 Q9UBN7 1/20 0.31
DPP4 P27487 1/20 0.31
AR P10275 1/20 0.31
CAPN1 P07384 1/20 0.30
MMP1 P03956 1/20 0.30
MMP3 P08254 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3021562 1.00 GFER (0.34) GFERRIPK1HDAC6DPP4AR
SCHEMBL3026154 0.92 LMNA (0.35) CAPN1
SCHEMBL3026151 0.92 LMNA (0.35) CAPN1
SCHEMBL2794405 0.87 GFER (0.39) GFERRIPK1HDAC6DPP4AR
SCHEMBL2794403 0.87 GFER (0.39) GFERRIPK1HDAC6DPP4AR
SCHEMBL3022436 0.86 GFER (0.35) GFERRIPK1HDAC6DPP4AR
SCHEMBL3022438 0.86 GFER (0.35) GFERRIPK1HDAC6DPP4AR
SCHEMBL3026764 0.84 ACHE (0.36) GFERMMP1MMP3MMP9
SCHEMBL3026763 0.84 ACHE (0.36) GFERMMP1MMP3MMP9
SCHEMBL3017186 0.82 XDH (0.42) GFERMMP1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100190794-A1 Herbicidally Active Composition BASF SE (DE) 2010-07-29 US claimed
EP-2157856-A1 HERBICIDALLY EFFECTIVE COMPOSITION Basf Se (DE) 2010-03-03 EP claimed
WO-2008152074-A1 HERBICIDALLY EFFECTIVE COMPOSITION BASF SE (DE) 2008-12-18 WO claimed
US-20100190794-A1 Herbicidally Active Composition BASF SE (DE) 2010-07-29 US disclosed
EP-2157856-A1 HERBICIDALLY EFFECTIVE COMPOSITION Basf Se (DE) 2010-03-03 EP disclosed
WO-2008152074-A1 HERBICIDALLY EFFECTIVE COMPOSITION BASF SE (DE) 2008-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100190794-A1 Herbicidally Active Composition ECI1, ACLY, SQOR GFER 47/4885RIPK1 3858/4885HDAC6 3120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.