Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.77 |
| ▸ | MMP9 | P14780 | 8/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.69 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991879 | 0.87 | MMP2 (1.00) | MMP2MMP9L3MBTL1 | |
| SCHEMBL27944763 | 0.84 | L3MBTL1 (0.69) | MMP2MMP9L3MBTL1CA12CA9 | |
| SCHEMBL28810693 | 0.84 | L3MBTL1 (0.79) | MMP2MMP9L3MBTL1CA12CA9 | |
| SCHEMBL27954385 | 0.80 | CA2 (0.76) | MMP2MMP9L3MBTL1CA12CA9 | |
| SCHEMBL28808747 | 0.75 | MMP2 (0.81) | MMP2MMP9L3MBTL1CA1CA2 | |
| SCHEMBL5856319 | 0.74 | PTGS1 (0.73) | MMP2MMP9L3MBTL1 | |
| SCHEMBL27991839 | 0.73 | MMP2 (0.75) | MMP2MMP9L3MBTL1CA1CA2 | |
| SCHEMBL16740663 | 0.71 | PRKCZ (1.00) | MMP2MMP9L3MBTL1CA12CA9 | |
| SCHEMBL18826388 | 0.70 | CA1 (0.91) | MMP2MMP9L3MBTL1CA12CA9 | |
| SCHEMBL5857978 | 0.70 | CA2 (0.56) | MMP2MMP9L3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664786-A | Synthesis method of dihydro-pyrazole sulfonamide derivatives of salicylaldehydes and application of dihydro-pyrazole sulfonamide derivatives to preparation of anticancer drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2014-03-26 | — | — | CN | disclosed |