Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 10/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972550 | 0.88 | GRM1 (0.43) | GRM1GRM4TRPV1KDM4E | |
| SCHEMBL27972308 | 0.86 | MEN1 (0.50) | KDM4E | |
| SCHEMBL28813208 | 0.85 | KDM4E (0.35) | GRM1GRM4TRPV1KDM4E | |
| SCHEMBL27972549 | 0.83 | SMO (0.53) | GRM4 | |
| SCHEMBL27972621 | 0.82 | NPC1 (0.42) | TRPV1KDM4E | |
| SCHEMBL27972606 | 0.80 | KDM4E (0.51) | KDM4E | |
| SCHEMBL28261342 | 0.79 | MEN1 (0.52) | KDM4E | |
| SCHEMBL27972271 | 0.79 | RAB9A (0.53) | KDM4E | |
| SCHEMBL27972318 | 0.79 | PTPN1 (0.48) | — | |
| SCHEMBL28866664 | 0.78 | PTPN1 (0.52) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104066724-A | P2X4 receptor antagonists | NIPPON CHEMIPHAR CO | 2014-09-24 | — | — | CN | disclosed |