Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.45 |
| ▸ | PPM1D | O15297 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28138572 | 0.98 | DAO (0.48) | DAOPPM1DKDM4CTBK1THRA | |
| SCHEMBL28133767 | 0.93 | GPR84 (0.38) | DAOPPM1DTBK1 | |
| SCHEMBL27712207 | 0.88 | MCL1 (0.41) | DAOPPM1DKDM4CTHRATHRB | |
| SCHEMBL14811147 | 0.78 | MRGPRX4 (0.40) | PPM1DRAB9AKMT2A | |
| SCHEMBL28139210 | 0.78 | CYP2C19 (0.43) | L3MBTL1KMT2A | |
| SCHEMBL19328863 | 0.77 | DAO (0.48) | DAOPPM1DTBK1THRATHRB | |
| SCHEMBL27692114 | 0.77 | LNPEP (0.37) | — | |
| SCHEMBL16749638 | 0.76 | CA12 (0.48) | DAOKMT2A | |
| SCHEMBL27692208 | 0.76 | LNPEP (0.36) | PPM1D | |
| SCHEMBL6565816 | 0.76 | GLRA3 (0.41) | DAOPPM1DTBK1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958508-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC | 2014-07-30 | — | — | CN | disclosed |