Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.48 |
| ▸ | PPM1D | O15297 | 2/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975645 | 0.98 | DAO (0.45) | DAOPPM1DKDM4CKMT2ATHRA | |
| SCHEMBL28133767 | 0.91 | GPR84 (0.38) | DAOPPM1DTBK1 | |
| SCHEMBL27712207 | 0.90 | MCL1 (0.41) | DAOPPM1DKDM4CKMT2ATHRA | |
| SCHEMBL19328863 | 0.79 | DAO (0.48) | DAOPPM1DTHRATHRBRAB9A | |
| SCHEMBL4649265 | 0.78 | DAO (0.37) | DAOPPM1DKDM4CEPHX2 | |
| SCHEMBL14811147 | 0.76 | MRGPRX4 (0.40) | PPM1DKMT2ARAB9A | |
| SCHEMBL28139210 | 0.76 | CYP2C19 (0.43) | KMT2AL3MBTL1 | |
| SCHEMBL27692114 | 0.76 | LNPEP (0.37) | MCL1 | |
| SCHEMBL2197741 | 0.75 | PPM1D (0.53) | PPM1DKDM4CKMOMCL1 | |
| SCHEMBL16749638 | 0.74 | CA12 (0.48) | DAOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074814-A | Glucose transport inhibitor | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106687455-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2017-05-17 | — | — | CN | disclosed |