Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | PPM1D | O15297 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975645 | 0.93 | DAO (0.45) | DAOPPM1DTBK1 | |
| SCHEMBL28138572 | 0.91 | DAO (0.48) | DAOPPM1DTBK1 | |
| SCHEMBL14811147 | 0.84 | MRGPRX4 (0.40) | PPM1DGAACA1CA2 | |
| SCHEMBL27692114 | 0.83 | LNPEP (0.37) | TPMT | |
| SCHEMBL27692208 | 0.82 | LNPEP (0.36) | PPM1D | |
| SCHEMBL27712207 | 0.81 | MCL1 (0.41) | GPR84DAOPPM1D | |
| SCHEMBL27580519 | 0.81 | ALDH1A1 (0.48) | GPR84PTGER4PTGER2MAOBGRIK1 | |
| SCHEMBL28139210 | 0.81 | CYP2C19 (0.43) | — | |
| SCHEMBL27782015 | 0.80 | GRIK1 (0.45) | PPM1DCA12CA1CA2CA7 | |
| SCHEMBL16749638 | 0.79 | CA12 (0.48) | DAOGAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458984-A | 5, 6-disubstituted pyridine-2-carboxamides as cannabinoid receptor agonists | 豪夫迈·罗氏有限公司 | 2017-02-22 | — | — | CN | disclosed |