Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSH | P09668 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068145 | 0.80 | CTSK (0.42) | CNR2MEN1KMT2ASMN1; SMN2CTSL | |
| SCHEMBL28290423 | 0.76 | LMNA (0.49) | CNR2MEN1KMT2A | |
| SCHEMBL1066498 | 0.73 | CTSS (0.40) | MEN1KMT2AHPGDSMN1; SMN2USP2 | |
| SCHEMBL2700635 | 0.73 | CTSS (0.40) | MEN1KMT2AHPGDSMN1; SMN2USP2 | |
| SCHEMBL10290412 | 0.72 | LMNA (0.54) | CNR2MEN1KMT2ASMN1; SMN2USP2 | |
| SCHEMBL26009956 | 0.71 | HPGD (0.45) | CNR2MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL29273401 | 0.70 | PRKCA (0.38) | MEN1KMT2ACTSLCTSBCTSK | |
| SCHEMBL27834087 | 0.70 | CPB2 (0.45) | MEN1KMT2ACTSLCTSBCTSH | |
| SCHEMBL28680208 | 0.69 | PRKCA (0.37) | — | |
| SCHEMBL29271806 | 0.69 | PRKCA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102007118-B | Pyrrolidinone glucokinase activators | HOFFMANN LA ROCHE | 2014-12-31 | — | — | CN | disclosed |