Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801832 | 0.79 | TSHR (0.52) | IDO1APPCACNA2D1CACNB2CACNA1C | |
| SCHEMBL2519799 | 0.79 | TSHR (0.52) | IDO1APPCACNA2D1CACNB2CACNA1C | |
| SCHEMBL17845069 | 0.79 | APP (0.48) | IDO1APPCACNA2D1CACNB2CACNA1C | |
| SCHEMBL8681264 | 0.73 | CYP1A1 (0.44) | IDO1APPCACNA2D1CACNB2CACNA1C | |
| SCHEMBL2683928 | 0.71 | CACNA2D1 (0.40) | IDO1APPCACNA2D1CACNB2CACNA1C | |
| SCHEMBL9669350 | 0.71 | HTR2A (0.40) | IDO1APPCACNA2D1CACNB2CACNA1C | |
| SCHEMBL2802726 | 0.71 | CACNA2D1 (0.40) | IDO1APPCACNA2D1CACNB2CACNA1C | |
| SCHEMBL2686081 | 0.71 | VCP (0.46) | IDO1APPCACNA2D1CACNB2CACNA1C | |
| SCHEMBL28599273 | 0.71 | AGTR1 (0.45) | IDO1APPGRM5LMNAKMT2A | |
| SCHEMBL8625450 | 0.70 | SRD5A2 (0.47) | CACNA2D1CACNB2CACNA1CGRM5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763734-B2 | Synthesis, structure and use of bisoxazolidines for asymmetric catalysis and synthesis | GEORGETOWN UNIVERSITY (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070265255-A1 | SYNTHESIS, STRUCTURE AND USE OF BISOXAZOLIDINES FOR ASYMMETRIC CATALYSIS AND SYNTHESIS | GEORGETOWN UNIVERSITY | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265255-A1 | SYNTHESIS, STRUCTURE AND USE OF BISOXAZOLIDINES FOR ASYMMETRIC CATALYSIS AND SYNTHESIS | ADH5, ADH1C, ADH1A | IDO1 649/4885APP 4389/4885CACNA2D1 2691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.