Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 2/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | CPA3 | P15088 | 1/20 | 0.55 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828973 | 0.90 | ALDH1A1 (0.52) | CPA1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL21214617 | 0.82 | CPA3 (0.57) | CPA3OPRM1OPRK1OPRD1HPGD | |
| SCHEMBL10010705 | 0.80 | LTA4H (0.50) | CPA3OPRM1OPRK1OPRD1LTA4H | |
| Acetic Acid SCHEMBL10591922 | 0.79 | CPA3 (0.51) | CPA3OPRM1OPRK1OPRD1HPGD | |
| Acetic Acid SCHEMBL10591913 | 0.79 | CPA3 (0.51) | CPA3OPRM1OPRK1OPRD1HPGD | |
| SCHEMBL7320183 | 0.79 | TRPA1 (0.53) | OPRM1OPRK1OPRD1 | |
| SCHEMBL5383411 | 0.79 | TRPA1 (0.53) | OPRM1OPRK1OPRD1 | |
| SCHEMBL7322626 | 0.79 | TRPA1 (0.53) | OPRM1OPRK1OPRD1 | |
| Acetic Acid SCHEMBL6276580 | 0.77 | OPRD1 (0.52) | OPRM1OPRK1OPRD1ALDH1A1LMNA | |
| SCHEMBL9915838 | 0.76 | OPRK1 (0.52) | OPRK1OPRD1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662015-B | Complement pathway modulators and uses thereof | 诺华股份有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-104662015-A | Complement pathway modulators and uses thereof | NOVARTIS AG | 2015-05-27 | — | — | CN | disclosed |