Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712093 | 0.84 | TRIM24 (0.47) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL18753527 | 0.80 | ALDH1A1 (0.42) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL7347117 | 0.79 | DRD1 (0.56) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL3688332 | 0.79 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1TSHRMAP2K7 | |
| Isopropylamine SCHEMBL28787289 | 0.78 | LMNA (0.46) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL30548758 | 0.77 | MAP2K7 (0.41) | LMNAKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL16307961 | 0.76 | MAP2K7 (0.31) | MAP2K7CDC25ACDC25BADRA2AADRA2B | |
| SCHEMBL173014 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL29517618 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL3196146 | 0.75 | KMT2A (0.60) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107177310-A | A kind of acrylic polysiloxane coating | 马鞍山采石矶涂料有限公司 | 2017-09-19 | — | — | CN | claimed |
| EP-4055085-B1 | HIGH TEMPERATURE RESISTANT DUAL COMPONENT SILICONE ADHESIVE | HENKEL AG & CO KGAA (DE) | 2026-01-21 | — | — | EP | disclosed |
| US-20240059820-A1 | Acrylate resins and Powder Coating Compositions and Powder Coated Substrates Including the Same | AKZO NOBEL COATINGS INTERNATINAL B.V. (NL) | 2024-02-22 | — | — | US | disclosed |
| US-20220259473-A1 | HIGH TEMPERATURE RESISTANT DUAL COMPONENT SILICONE ADHESIVE | HENKEL AG & CO KGAA (DE) | 2022-08-18 | — | — | US | disclosed |
| EP-3110894-B1 | ACRYLIC RESINS AND POWDER COATING COMPOSITIONS AND POWDER COATED SUBSTRATES INCLUDING THE SAME | AKZO NOBEL COATINGS INT BV (NL) | 2021-08-18 | — | — | EP | disclosed |
| CN-110423595-A | A kind of full fitting intelligent blackboard | JIANGSU FANPU INFORMATION TECH CO LTD | 2019-11-08 | — | — | CN | disclosed |
| CN-108997981-A | Bi-component curing type phase change heat storage material and preparation method thereof | 南方科技大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-107177310-A | A kind of acrylic polysiloxane coating | 马鞍山采石矶涂料有限公司 | 2017-09-19 | — | — | CN | disclosed |
| US-9718849-B2 | Sulfur chelated ruthenium compounds useful as olefin metathesis catalysts | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2017-08-01 | — | — | US | disclosed |
| EP-2655303-B1 | HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH TETRADENTATE AMINO/IMINO-THIOETHER BASED RUTHENIUM COMPLEXES | FIRMENICH & CIE (CH) | 2017-02-22 | — | — | EP | disclosed |
| WO-2005079270-A2 | 2-SUBSTITUTED AND 4-SUBSTITUTED ARYL NITRONE COMPOUDS | RENOVIS, INC. (US) | 2005-09-01 | — | — | WO | disclosed |
| US-20050182060-A1 | 2-Substituted and 4-substituted aryl nitrone compounds | RENOVIS, INC. | 2005-08-18 | — | — | US | disclosed |
| US-20050059638-A1 | Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders | RENOVIS, INC. | 2005-03-17 | — | — | US | disclosed |
| WO-2005016272-A2 | ARYL, HETEROAROMATIC AND BICYCLIC ARYL NITRONE COMPOUNDS, PRODRUGS AND PHARMACEUTICAL COMPOSITIONS OF THE SAME TO TREAT HUMAN DISORDERS | RENOVIS, INC. (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20040192680-A1 | Novel amides that activate soluble guanylate cyclase | ABBOTT LABORATORIES | 2004-09-30 | — | — | US | disclosed |
| WO-2004060859-A2 | NOVEL AMIDES THAT ACTIVATE SOLUBLE GUANYLATE CYCLASE | ABBOTT LABORATORIES (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20040121994-A1 | Novel amides that activate soluble guanylate cyclase | ABBOTT LABORATORIES | 2004-06-24 | — | — | US | disclosed |
| EP-0572712-B1 | Processes for producing 2-substituted benzo(beta)thiophene | SUMITOMO SEIKA CHEMICALS (JP) | 1998-01-21 | — | — | EP | disclosed |
| US-5298630-A | Reacting 2-alkylthiobenzaldehyde derivative with halo compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0572712-A2 | Processes for producing 2-substituted benzo(beta)thiophene | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1993-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059638-A1 | Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders | AHR, NAT1, ARNT | LMNA 2903/4885KMT2A 2587/4885MEN1 4317/4885 |
| US-20040121994-A1 | Novel amides that activate soluble guanylate cyclase | GUCY1A1, GUCY1B1, GUCY1A2 | LMNA 2027/4885KMT2A 3702/4885MEN1 1311/4885 |
| US-20040192680-A1 | Novel amides that activate soluble guanylate cyclase | GUCY1A1, GUCY1B1, GUCY1A2 | LMNA 2027/4885KMT2A 3702/4885MEN1 1311/4885 |
| US-20050182060-A1 | 2-Substituted and 4-substituted aryl nitrone compounds | CXCR2, CCL5, CCL2 | LMNA 3216/4885KMT2A 4071/4885MEN1 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.