Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL6581224 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAHSD17B10MAPK1 | |
| Ether SCHEMBL1797 | 1.00 | — | — | |
| Ether SCHEMBL27267758 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAHSD17B10MAPK1 | |
| Ether SCHEMBL9058622 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAHSD17B10MAPK1 | |
| Ether SCHEMBL9688867 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAHSD17B10MAPK1 | |
| Ether SCHEMBL9321955 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAHSD17B10MAPK1 | |
| Ether SCHEMBL5693230 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAHSD17B10MAPK1 | |
| Ether SCHEMBL5597265 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAHSD17B10MAPK1 | |
| Ether SCHEMBL11664156 | 0.96 | — | — | |
| Ether SCHEMBL1280469 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230404877-A1 | POWDER-CONTAINING COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2023-12-21 | — | — | US | disclosed |
| US-20230293417-A1 | ADENOSINE-CONTAINING COMPOSITION AND METHOD FOR SUPPRESSING PRECIPITATION OF ADENOSINE | SHISEIDO COMPANY, LTD. (JP) | 2023-09-21 | — | — | US | disclosed |
| EP-3666251-B1 | POWDER-CONTAINING WATER-BASED COMPOSITION AND EXTERNAL SKIN PREPARATION | SHISEIDO CO LTD (JP) | 2023-09-06 | — | — | EP | disclosed |
| US-11730684-B2 | Cleansing composition | SHISEIDO COMPANY, LTD. (JP) | 2023-08-22 | — | — | US | disclosed |
| US-20230190626-A1 | CLEANSER COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2023-06-22 | — | — | US | disclosed |
| US-20230190590-A1 | LAMELLAR GEL-CONTAINING COMPOSITION, EMULSIFIED COMPOSITION, AND COMPOSITION FOR EXTERNAL-USE SKIN PREPARATION | SHISEIDO COMPANY, LTD. (JP) | 2023-06-22 | — | — | US | disclosed |
| US-20230142992-A1 | THICKENER FOR NON-AQUEOUS COMPOSITIONS | SHISEIDO COMPANY, LTD. (JP) | 2023-05-11 | — | — | US | disclosed |
| EP-4151280-A1 | CLEANSER COMPOSITION | Shiseido Company, Ltd. (JP) | 2023-03-22 | — | — | EP | disclosed |
| EP-4134067-A1 | LAMELLAR GEL-CONTAINING COMPOSITION, EMULSIFIED COMPOSITION, AND COMPOSITION FOR AGENT FOR EXTERNAL USE ON SKIN | Shiseido Company, Ltd. (JP) | 2023-02-15 | — | — | EP | disclosed |
| US-11572484-B2 | Ink-jet ink composition, ink-jet cartridge, and decoration device | SHISEIDO COMPANY, LTD. (JP) | 2023-02-07 | — | — | US | disclosed |
| EP-2027849-A1 | EXTERNAL PREPARATION FOR SKIN | Shiseido Company, Limited (JP) | 2009-02-25 | — | — | EP | disclosed |
| EP-1104416-A2 | QUATERNARY AMMONIUM SALTS AND THEIR USE AS ANTI-HIV AGENTS | Takeda Chemical Industries, Ltd. (JP) | 2001-06-06 | — | — | EP | disclosed |
| EP-1039899-A2 | PHARMACEUTICAL COMPOSITION FOR ANTAGONIZING CCR5 COMPRISING ANILIDE DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-1040103-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| WO-2000010965-A2 | QUATERNARY AMMONIUM SALTS AND THEIR USE AS ANTI-HIV AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-02 | — | — | WO | disclosed |
| WO-1999032100-A2 | PHARMACEUTICAL COMPOSITION FOR ANTAGONIZING CCR5 COMPRISING ANILIDE DERIVATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |
| WO-1999032468-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |
| EP-0322976-B1 | Polymeric polyalcohols | SHELL INT RESEARCH (NL) | 1998-02-18 | — | — | EP | disclosed |
| EP-0322976-A2 | Polymeric polyalcohols | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-07-05 | — | — | EP | disclosed |
| WO-1982001085-A1 | BILAYER PHOTOSENSITIVE IMAGING ARTICLE | NAPP SYSTEMS INC (US) | 1982-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11730684-B2 | Cleansing composition | DEGS1, SGMS2, SGMS1 | ALDH1A1 3920/4885TSHR 4822/4885LMNA 916/4885 |
| US-20230190626-A1 | CLEANSER COMPOSITION | MGLL, SGMS2, DAGLB | ALDH1A1 3099/4885TSHR 4218/4885LMNA 2227/4885 |
| US-20230142992-A1 | THICKENER FOR NON-AQUEOUS COMPOSITIONS | DSG1, AQP1, STOM | ALDH1A1 4801/4885TSHR 4109/4885LMNA 3537/4885 |
| US-20230190590-A1 | LAMELLAR GEL-CONTAINING COMPOSITION, EMULSIFIED COMPOSITION, AND COMPOSITION FOR EXTERNAL-USE SKIN PREPARATION | CUTA, EBP, LIPA | ALDH1A1 1791/4885TSHR 4668/4885LMNA 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.