Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998377 | 0.85 | ALDH1A1 (0.41) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL28015666 | 0.83 | ALDH1A1 (0.37) | RAB9ANPC1ALDH1A1KDM4EPTGS1 | |
| SCHEMBL28015735 | 0.81 | RAB9A (0.37) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL16762229 | 0.81 | ALDH1A1 (0.44) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL28015158 | 0.77 | HSD11B1 (0.38) | RAB9ANPC1KDM4EHPGDHSD17B10 | |
| SCHEMBL28015710 | 0.75 | IKBKE (0.39) | RAB9ANPC1HSD11B1PTGS1PTGS2 | |
| SCHEMBL2615997 | 0.71 | LMNA (0.61) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL28015149 | 0.71 | NPC1 (0.46) | RAB9ANPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28015664 | 0.70 | HSD11B1 (0.40) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL28015705 | 0.69 | KDM4E (0.38) | RAB9ANPC1ALDH1A1KDM4EMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |