Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HK1 | P19367 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015710 | 0.84 | IKBKE (0.39) | ADORA3MGAMGAASIMGAM2 | |
| SCHEMBL2165945 | 0.80 | KDM4E (0.38) | KDM4EADORA3MGAMGAASI | |
| SCHEMBL28015666 | 0.75 | ALDH1A1 (0.37) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL28015158 | 0.74 | HSD11B1 (0.38) | KDM4EMAPTHTTNPC1RAB9A | |
| SCHEMBL16720191 | 0.73 | KDM4E (0.38) | KDM4EADORA3MGAMGAASI | |
| SCHEMBL6826494 | 0.71 | MAP4K4 (0.39) | KDM4EADORA3MAPTMEN1KMT2A | |
| SCHEMBL2093692 | 0.71 | ADORA2A (0.43) | KDM4EADORA3MGAMGAASI | |
| SCHEMBL28819179 | 0.70 | ADORA3 (0.49) | KDM4EADORA3MGAMGAASI | |
| SCHEMBL28015656 | 0.69 | RAB9A (0.36) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL6825688 | 0.69 | MAP4K4 (0.37) | KDM4EADORA3MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |