Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27938376 | 0.80 | ASPH (0.36) | PPARAPPARGKMO | |
| SCHEMBL28119309 | 0.77 | ALDH1A1 (0.36) | KDM4EALDH1A1POLBMAPTLMNA | |
| SCHEMBL28119307 | 0.76 | PRKAB2 (0.34) | KMO | |
| SCHEMBL28260791 | 0.75 | LTB4R (0.34) | PPARAPPARGPPARDKDM4ENPC1 | |
| SCHEMBL21750637 | 0.74 | ALDH1A1 (0.36) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL22283908 | 0.73 | KMO (0.37) | KDM4EGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL8011712 | 0.72 | PPARA (0.42) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL28118987 | 0.71 | KDM4E (0.39) | PPARAPPARGKDM4EALDH1A1TSHR | |
| SCHEMBL997135 | 0.70 | GABRP (0.44) | KDM4EGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL28026218 | 0.70 | NEK2 (0.35) | KDM4EMAPTSMN1; SMN2KMOTPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955808-A | Method of preparation of crystal forms of 4-(cyclopropylmethoxy)-n-(3,5-dichloro-1-oxidopyridyn-4-yl)-5-methoxypyridine-2-carboxamide and cristal forms thereof | SANOFI SA | 2015-09-30 | — | — | CN | disclosed |
| CN-104955820-A | Process for preparing 4-(cyclopropylmethoxy)-n-(3,5-dichloro-1-oxido-4-pyridyl)-5-methoxypyridine-2-carboxamide | SAI NUOFEI | 2015-09-30 | — | — | CN | disclosed |