SCHEMBL28032689

SCHEMBL28032689

CCC(Cc1ccccc1)(C(=O)c1ccc(Sc2ccc(C(C)C)cc2)cc1)N(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.40
RAB9A P51151 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 2/20 0.39
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
CNR2 P34972 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
USP5 P45974 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
AGBL2 Q5U5Z8 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
EPHX1 P07099 1/20 0.34
MLYCD O95822 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRB2 P47870 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28033176 0.87 ALDH1A1 (0.39) RAB9ANPC1ALDH1A1HPGDKDM4E
SCHEMBL4423938 0.83 MLYCD (0.38) SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL8897938 0.83 TAS2R14 (0.43) RAB9ASMN1; SMN2NPC1ALDH1A1HPGD
SCHEMBL4414354 0.82 OPRD1 (0.40) ALDH1A1CNR2MEN1KMT2AMLYCD
SCHEMBL8899758 0.81 PPARG (0.48) RAB9ANPC1MEN1KMT2AL3MBTL1
SCHEMBL4650526 0.81 RIPK1 (0.43) RAB9ASMN1; SMN2NPC1MEN1KMT2A
Benzene SCHEMBL28672020 0.81 RIPK1 (0.43) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL8899130 0.81 NPSR1 (0.41) RAB9ASMN1; SMN2NPC1ALDH1A1HPGD
SCHEMBL8898813 0.79 HDAC1 (0.37) RAB9ANPC1ALDH1A1HPGDNPSR1
SCHEMBL4651747 0.79 NPC1 (0.41) RAB9ASMN1; SMN2NPC1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104974053-A Novel aminoketones photoinitiator and application in UV-LED photocuring system TIANJIN JIURI CHEMICAL CO LTD 2015-10-14 CN disclosed