SCHEMBL280327

SCHEMBL280327

CC(=O)CCCCCCCCCCCN(C)C

nearest known ligand 0.70

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 3/20 0.70
ALDH1A1 P00352 1/20 0.55
TSHR P16473 1/20 0.55
KDM4A O75164 12/20 0.52
KDM4C Q9H3R0 12/20 0.52
KDM5A P29375 1/20 0.52
KDM7A Q6ZMT4 1/20 0.52
PHF8 Q9UPP1 1/20 0.52
KDM2A Q9Y2K7 1/20 0.52
DNM1 Q05193 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12248451 1.00 PAOX (0.70) PAOXALDH1A1TSHRKDM4AKDM4C
SCHEMBL25907273 1.00 PAOX (0.70) PAOXALDH1A1TSHRKDM4AKDM4C
SCHEMBL18154617 1.00 PAOX (0.70) PAOXALDH1A1TSHRKDM4AKDM4C
SCHEMBL2036849 0.97 PAOX (0.67) PAOXALDH1A1TSHRKDM4AKDM4C
SCHEMBL805274 0.90
SCHEMBL16359464 0.83 DNM1 (0.68) PAOXKDM4AKDM4CKDM5AKDM7A
Acetic Acid SCHEMBL19856511 0.81 ALDH1A1 (0.65) PAOXALDH1A1TSHRKDM4AKDM4C
SCHEMBL22788743 0.81 PAOX (0.50) PAOXALDH1A1KDM4AKDM4CKDM5A
SCHEMBL16723870 0.81 PAOX (0.72) PAOXALDH1A1TSHR
SCHEMBL2775487 0.81 PAOX (0.72) PAOXALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9901565-B2 Membrane fusion inhibitor PROTECTEA, LTD. (JP) 2018-02-27 US disclosed
US-9801850-B2 Antibacterial agent OSAKA UNIVERSITY (JP) 2017-10-31 US disclosed
US-20150111961-A1 MEMBRANE FUSION INHIBITOR PROTECTEA, LTD. (JP) 2015-04-23 US disclosed
US-8952055-B2 Membrane fusion inhibitor PROTECTEA, LTD. (JP) 2015-02-10 US disclosed
US-20120136049-A1 ANTIBACTERIAL AGENT OSAKA UNIVERSITY (JP) 2012-05-31 US disclosed
US-8133985-B2 Peptide nucleic acids conjugated with multi-amine linkers and nucleic acid detecting device using the same PANAGENE INC. (KR) 2012-03-13 US disclosed
US-20110003889-A1 MEMBRANE FUSION INHIBITOR KAIHATSU, Kunihiro (JP) 2011-01-06 US disclosed
US-20090312197-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME PANAGENE INC. (KR) 2009-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312197-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME NPPA, PARN, PARG PAOX 3489/4885ALDH1A1 3477/4885TSHR 423/4885
US-20120136049-A1 ANTIBACTERIAL AGENT TEAD4, ELOVL6, TEAD1 PAOX 2998/4885ALDH1A1 677/4885TSHR 2877/4885
US-20150111961-A1 MEMBRANE FUSION INHIBITOR FLOT1, NSF, VAMP7 PAOX 3935/4885ALDH1A1 2332/4885TSHR 2134/4885
US-20110003889-A1 MEMBRANE FUSION INHIBITOR FLOT1, NSF, VAMP7 PAOX 3935/4885ALDH1A1 2332/4885TSHR 2134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.