Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IL18 | Q14116 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063720 | 0.86 | POLB (0.46) | GAAMAPTALDH1A1PARP10TSHR | |
| SCHEMBL4299441 | 0.80 | MGLL (0.47) | GAASMN1; SMN2ALDH1A1MMP2MMP3 | |
| SCHEMBL9658504 | 0.79 | TAS1R3 (0.53) | SMN1; SMN2MAPTALDH1A1PARP10PARP2 | |
| SCHEMBL13763456 | 0.79 | LMNA (0.53) | MAPTALDH1A1PARP10TSHRMEN1 | |
| SCHEMBL9260198 | 0.78 | MMP2 (0.49) | GAASMN1; SMN2MAPTALDH1A1MMP2 | |
| SCHEMBL9251385 | 0.78 | MMP2 (0.49) | GAASMN1; SMN2MAPTALDH1A1MMP2 | |
| SCHEMBL4104288 | 0.77 | MAPT (0.51) | GAASMN1; SMN2MAPTALDH1A1MMP2 | |
| SCHEMBL4763620 | 0.77 | LDHA (0.52) | GAASMN1; SMN2MAPTALDH1A1PARP10 | |
| SCHEMBL28492939 | 0.77 | CYP1A2 (0.46) | GAASMN1; SMN2MAPTTSHRMEN1 | |
| SCHEMBL28045207 | 0.77 | CYP19A1 (0.42) | GAASMN1; SMN2ALDH1A1PARP10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051037-A | Sphingosine-1-phosphate receptor agonists, method for the preparation thereof and pharmaceutical compositions comprising the same as active agent | LG LIFE SCIENCES LTD | 2015-11-11 | — | — | CN | disclosed |