Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751878 | 0.82 | CYP1A2 (0.49) | GAASMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL28037643 | 0.80 | GAA (0.48) | MGLLGAASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL4298297 | 0.80 | MGLL (0.46) | MGLLALDH1A1CYP2C19 | |
| SCHEMBL4750352 | 0.78 | RAB9A (0.55) | HRH2HRH1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL4753413 | 0.77 | TDP1 (0.51) | GAASMN1; SMN2 | |
| SCHEMBL4380069 | 0.75 | GPR119 (0.65) | HRH3GPR119 | |
| SCHEMBL4753498 | 0.74 | ALDH1A1 (0.48) | GAASMN1; SMN2ALDH1A1MAPK1CYP2C19 | |
| SCHEMBL4750109 | 0.72 | ALDH1A1 (0.40) | MGLLGAASMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL4293429 | 0.72 | FKBP1A (0.48) | MGLLGAAALDH1A1HSD17B10 | |
| SCHEMBL4751893 | 0.71 | MGLL (0.42) | MGLLSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227560-A1 | Substituted imidazole compound and use thereof | REN, ACE, AGT | MGLL 2197/4885PANK3 1934/4885HRH3 1248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.