Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040821 | 0.83 | GPR3 (0.39) | HSD11B1GPR3PTPN1 | |
| SCHEMBL27953352 | 0.81 | HSD11B1 (0.44) | HSD11B1PSMB5CA2CA1TRPV1 | |
| SCHEMBL28040845 | 0.78 | LMNA (0.32) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27942530 | 0.76 | CA2 (0.42) | HSD11B1CA2CA1ALDH1A1HPGD | |
| SCHEMBL28040770 | 0.75 | PTAFR (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27953350 | 0.74 | HSD11B1 (0.39) | HSD11B1PSMB5CNR2CA2CA1 | |
| SCHEMBL28040823 | 0.69 | LOXL2 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27942528 | 0.69 | HSD11B1 (0.39) | HSD11B1CA2CA1ALDH1A1HPGD | |
| SCHEMBL10317156 | 0.69 | HSD11B1 (0.43) | HSD11B1PSMB5CNR2CA2CA1 | |
| SCHEMBL10319997 | 0.69 | HSD11B1 (0.43) | HSD11B1PSMB5CNR2CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |