Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040821 | 0.84 | GPR3 (0.39) | L3MBTL1 | |
| SCHEMBL28040845 | 0.79 | LMNA (0.32) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL28040843 | 0.79 | MAPT (0.39) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL28040823 | 0.78 | LOXL2 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28040359 | 0.76 | PTAFR (0.34) | PTAFRNPC1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL28823631 | 0.76 | CDC25A (0.35) | — | |
| SCHEMBL28040416 | 0.75 | HSD11B1 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28040608 | 0.72 | LMNA (0.34) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL28040418 | 0.71 | CDC25A (0.33) | ALDH1A1LMNAMAPTSMN1; SMN2TP53 | |
| SCHEMBL28040414 | 0.67 | ESR1 (0.38) | PTAFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |