Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040412 | 0.83 | GPR3 (0.41) | LMNAALDH1A1L3MBTL1SETD7TP53 | |
| SCHEMBL28823624 | 0.76 | LOXL2 (0.39) | ALDH1A1SMN1; SMN2CYP3A4HTR6 | |
| SCHEMBL27886299 | 0.75 | LMNA (0.39) | LMNAMAPTALDH1A1SETD7TP53 | |
| SCHEMBL28040419 | 0.74 | ALDH1A1 (0.34) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL28040837 | 0.74 | KDM4E (0.31) | LMNAMAPTALDH1A1ALOX15MEN1 | |
| SCHEMBL28040843 | 0.74 | MAPT (0.39) | LMNAMAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL27953350 | 0.74 | HSD11B1 (0.39) | LMNAALDH1A1SMN1; SMN2SETD7TP53 | |
| SCHEMBL28040770 | 0.72 | PTAFR (0.33) | LMNAMAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL8079478 | 0.71 | LMNA (0.39) | LMNAMAPTALDH1A1SETD7TP53 | |
| SCHEMBL8080819 | 0.70 | SETD7 (0.39) | LMNAMAPTALDH1A1SETD7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |