Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.38 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10529916 | 0.70 | PTGS2 (0.47) | METTL3PTGS2CLCN2CLIC1CXCL8 | |
| SCHEMBL4434232 | 0.68 | METTL3 (0.76) | METTL3PTGS2CLCN2CLIC1CXCL8 | |
| Acetic Acid SCHEMBL16049910 | 0.68 | METTL3 (0.71) | METTL3PTGS2CLCN2CLIC1CXCL8 | |
| Hydrochloric Acid SCHEMBL2582024 | 0.67 | METTL3 (0.74) | METTL3PTGS2CLCN2MAPK1MEN1 | |
| SCHEMBL7576854 | 0.63 | PTGS2 (0.51) | METTL3PTGS2CLCN2CLIC1CXCL8 | |
| SCHEMBL8611754 | 0.63 | ALDH1A1 (0.62) | METTL3PTGS2CLCN2CLIC1CXCL8 | |
| SCHEMBL453815 | 0.63 | TSHR (0.71) | MEN1CHRM1KMT2AALDH1A1LMNA | |
| SCHEMBL10533120 | 0.63 | PTGS2 (0.52) | METTL3PTGS2CLCN2CLIC1CXCL8 | |
| Propanocaine SCHEMBL24544 | 0.62 | UTS2R (0.54) | CHRM1ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| Propanocaine SCHEMBL24545 | 0.62 | UTS2R (0.54) | CHRM1ALDH1A1LMNASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521305-A | Novel high-penetration medicine for treating Parkinson's disease and medicine composition thereof | 苏州泰飞尔医药有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-105143174-A | Novel high penetration drugs and pharmaceutical compositions for the treatment of parkinson's disease | TECHFIELDS PHARMA CO LTD | 2015-12-09 | — | — | CN | disclosed |