Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25338592 | 0.81 | ALDH1A1 (0.40) | GAAMEN1KMT2AALDH1A1TRPA1 | |
| SCHEMBL28225285 | 0.79 | ALDH1A1 (0.39) | GAAMEN1KMT2AALDH1A1TRPA1 | |
| SCHEMBL27464792 | 0.76 | GAA (0.43) | GAAMEN1KMT2AALDH1A1TRPA1 | |
| SCHEMBL27703943 | 0.74 | CA2 (0.40) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28188877 | 0.74 | CPB2 (0.41) | GAAMEN1KMT2AALDH1A1TRPA1 | |
| SCHEMBL28157967 | 0.74 | MMP1 (0.38) | GAAMEN1KMT2AALDH1A1TRPA1 | |
| SCHEMBL9734583 | 0.73 | L3MBTL1 (0.49) | GAAKMT2AALDH1A1TRPA1LMNA | |
| SCHEMBL8930120 | 0.72 | MEN1 (0.36) | GAAMEN1KMT2AALDH1A1TRPA1 | |
| SCHEMBL10782325 | 0.72 | ALDH1A1 (0.43) | GAAMEN1KMT2AALDH1A1TRPA1 | |
| SCHEMBL10369042 | 0.70 | PGR (0.42) | GAAMEN1KMT2AALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130834-B | A kind of preparation method of β amidos alpha amino acid ester derivative | 中国科学院兰州化学物理研究所 | 2017-06-23 | — | — | CN | disclosed |
| CN-105130834-A | Preparation method of beta-amido-alpha-amino-acid ester derivative | LANZHOU CHEM PHYS INST | 2015-12-09 | — | — | CN | disclosed |