SCHEMBL2804860

SCHEMBL2804860

CCCCCC(=O)Oc1ccc(C(=O)C=Cc2ccc(OC)cc2)c(O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.68
ABCG2 Q9UNQ0 5/20 0.68
MAPT P10636 5/20 0.68
LMNA P02545 3/20 0.68
MEN1 O00255 3/20 0.68
MAPK1 P28482 3/20 0.68
KMT2A Q03164 3/20 0.68
CYP3A4 P08684 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
CYP2C19 P33261 2/20 0.68
ALDH1A1 P00352 2/20 0.65
HPGD P15428 2/20 0.65
ALOX15 P16050 2/20 0.65
HSD17B10 Q99714 2/20 0.65
TP53 P04637 1/20 0.65
MAOB P27338 5/20 0.60
CTSL P07711 1/20 0.60
NPC1 O15118 1/20 0.59
RECQL P46063 1/20 0.59
RAB9A P51151 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2804858 1.00 APP (0.68) APPABCG2MAPTLMNAMEN1
SCHEMBL32662671 1.00 APP (0.68) APPABCG2MAPTLMNAMEN1
SCHEMBL30383182 1.00 APP (0.68) APPABCG2MAPTLMNAMEN1
SCHEMBL25195126 0.85 CYP3A4 (0.62) APPABCG2MAPTLMNAMEN1
SCHEMBL32662657 0.85 CYP3A4 (0.62) APPABCG2MAPTLMNAMEN1
SCHEMBL10828123 0.83 F3 (0.66) ABCG2MAPTLMNAMEN1MAPK1
SCHEMBL10828126 0.83 F3 (0.66) ABCG2MAPTLMNAMEN1MAPK1
SCHEMBL634187 0.82 ABCG2 (1.00) APPABCG2MAPTLMNAMEN1
SCHEMBL30384538 0.82 ABCG2 (1.00) APPABCG2MAPTLMNAMEN1
SCHEMBL25189208 0.82 ABCG2 (1.00) APPABCG2MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
EP-2538914-B1 COSMETIC COMPOSITION COMPRISING A SUPERABSORBENT POLYMER AND AT LEAST A GEMINI SURFACTANT ORÉAL L (FR) 2016-06-15 EP disclosed
US-9364690-B2 Composition comprising a superabsorbent polymer and a gemini surfactant L'OREAL (FR) 2016-06-14 US disclosed
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME OREAL (FR) 2016-03-10 US disclosed
US-20150224046-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT L'OREAL (FR) 2015-08-13 US disclosed
EP-2482793-B1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT ORÉAL L (FR) 2015-04-22 EP disclosed
US-8716311-B2 Use of piperidine ester derivative as solvent in cosmetic compositions; cosmetic compositions comprising it L'OREAL (FR) 2014-05-06 US disclosed
US-20140056832-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME L'OREAL (FR) 2014-02-27 US disclosed
US-20130039963-A1 COMPOSITION COMPRISING A SUPERABSORBENT POLYMER AND A GEMINI SURFACTANT L'OREAL (FR) 2013-02-14 US disclosed
US-20120282197-A1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'OREAL (FR) 2012-11-08 US disclosed
US-20120269746-A1 USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'OREAL (FR) 2012-10-25 US disclosed
US-20100330018-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT L'OREAL (FR) 2010-12-30 US disclosed
US-20100143276-A1 Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions L'OREAL (FR) 2010-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140056832-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME DIMT1, MAT2A, SCD APP 2985/4885ABCG2 1962/4885MAPT 3962/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B APP 794/4885ABCG2 1606/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 APP 1340/4885ABCG2 3622/4885MAPT 3512/4885
US-20150224046-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT KRT18, FABP2, FABP4 APP 2596/4885ABCG2 103/4885MAPT 159/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 APP 1340/4885ABCG2 3622/4885MAPT 3512/4885
US-20120282197-A1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT PLD1, PLD2, FFAR1 APP 1444/4885ABCG2 1174/4885MAPT 4114/4885
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME DIMT1, FADS2, SCD APP 2842/4885ABCG2 1754/4885MAPT 3804/4885
US-20100330018-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT KRT18, FABP2, FABP4 APP 2596/4885ABCG2 103/4885MAPT 159/4885
US-20120269746-A1 USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT DEGS1, CAPN1, PPT1 APP 1231/4885ABCG2 2578/4885MAPT 2822/4885
US-20100143276-A1 Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions FASN, ALOX12, PAH APP 1952/4885ABCG2 1382/4885MAPT 3479/4885
US-20130039963-A1 COMPOSITION COMPRISING A SUPERABSORBENT POLYMER AND A GEMINI SURFACTANT SGMS2, SGMS1, SCO2 APP 3729/4885ABCG2 2642/4885MAPT 4476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.