Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.48 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177141 | 0.81 | RAB9A (0.68) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL28049928 | 0.79 | RAB9A (0.54) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4740747 | 0.79 | RAB9A (0.64) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL28049871 | 0.77 | L3MBTL1 (0.72) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5213995 | 0.76 | KCNQ3 (0.77) | RAB9ASMN1; SMN2TDP1KCNQ3KCNQ2 | |
| SCHEMBL1986996 | 0.76 | KCNQ3 (0.82) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5215207 | 0.76 | KCNQ3 (0.81) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL10098561 | 0.75 | NNMT (0.51) | SMN1; SMN2ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL3313800 | 0.75 | RAB9A (0.75) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL1844238 | 0.74 | RAB9A (0.74) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601563-A | 6-chloro-N-(4-(6-chloro-nicotinamide)benzyl) nicotinamide, and preparation and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2016-05-25 | — | — | CN | disclosed |