Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049947 | 0.81 | HTT (0.51) | ATMHTTPOLBRXFP1NPC1 | |
| SCHEMBL10512809 | 0.81 | SAE1 (0.51) | NR4A2ATMHTTPOLBRXFP1 | |
| SCHEMBL13757489 | 0.79 | TRPA1 (0.56) | ATMEGFRLCK | |
| SCHEMBL15483521 | 0.77 | ALDH1A1 (0.36) | HTTRXFP1PKMHSD17B10KDM4E | |
| SCHEMBL7810629 | 0.76 | KDM4E (0.53) | ATMNPC1RAB9AEGFRKDM4E | |
| SCHEMBL21348272 | 0.75 | NR4A2 (0.46) | NR4A2HTTPOLBRXFP1NPC1 | |
| SCHEMBL13409356 | 0.74 | LMNA (0.56) | NR4A2POLBNPC1PKMALOX15 | |
| SCHEMBL20782877 | 0.72 | LCK (0.57) | EGFRLCKPDE1B | |
| SCHEMBL13783329 | 0.72 | RXFP1 (0.49) | NR4A2HTTPOLBRXFP1NPC1 | |
| SCHEMBL401110 | 0.71 | PDE4A (0.57) | NR4A2HTTRXFP1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294578-A | Quinazoline derivative having targeted antitumor activity | GUANGDONG WHOLEWIN TECHNOLOGY CO LTD | 2016-02-03 | — | — | CN | disclosed |