Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052294 | 0.77 | KLKB1 (0.40) | KLKB1 | |
| SCHEMBL28074772 | 0.76 | CTSK (0.36) | — | |
| SCHEMBL28045792 | 0.68 | MAOA (0.36) | — | |
| SCHEMBL17229326 | 0.68 | KLKB1 (0.46) | KLKB1KLK1 | |
| SCHEMBL16486803 | 0.67 | KLKB1 (0.48) | KLKB1KLK1 | |
| SCHEMBL15759268 | 0.66 | KLKB1 (0.51) | KLKB1KLK1 | |
| SCHEMBL28824696 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL13813853 | 0.63 | KCNH2 (0.53) | KLKB1 | |
| SCHEMBL17232474 | 0.63 | KLKB1 (0.49) | KLKB1KLK1 | |
| SCHEMBL16246747 | 0.63 | KLKB1 (0.49) | KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452240-A | Heterocyclic derivates | KALVISTA PHARMACEUTICALS LTD | 2016-03-30 | — | — | CN | disclosed |