Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301856 | 0.77 | ALDH1A1 (0.50) | PTGDR2KDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL330292 | 0.76 | PTGDR2 (0.55) | PTGDR2KDM4EPOLBCYP1A2ALDH1A1 | |
| SCHEMBL3185311 | 0.75 | CALM1 (0.39) | PTGDR2KDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL468178 | 0.71 | GPR84 (0.43) | HSD17B10ALDH1A1MAPT | |
| SCHEMBL10281014 | 0.70 | PTGDR2 (0.48) | PTGDR2KDM4EPOLBCYP1A2HSD17B10 | |
| SCHEMBL3277726 | 0.68 | TRPM8 (0.55) | CYP1A2HSD17B10ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL330399 | 0.67 | ALDH1A1 (0.44) | KDM4ECYP1A2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL1663243 | 0.67 | PTGDR2 (0.39) | PTGDR2KDM4EPOLBCYP1A2HSD17B10 | |
| SCHEMBL331177 | 0.66 | RARA (0.40) | KDM4EPOLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL557950 | 0.66 | KDM4E (0.42) | KDM4ECYP1A2ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776537-A | Purinedione as WNT pathway modulators | 新加坡科技研究局 | 2019-05-21 | — | — | CN | disclosed |
| CN-105452248-A | Purine diones as WNT pathway modulators | AGENCY SCIENCE TECH & RES | 2016-03-30 | — | — | CN | disclosed |