Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061589 | 0.79 | SLC6A3 (0.35) | LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28061573 | 0.76 | ALDH1A1 (0.41) | LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28061544 | 0.75 | LMNA (0.39) | LMNA | |
| SCHEMBL28061570 | 0.74 | EPHX2 (0.33) | — | |
| SCHEMBL28061564 | 0.69 | LIPE (0.35) | — | |
| SCHEMBL3542512 | 0.66 | EPHX2 (0.32) | — | |
| SCHEMBL17029320 | 0.66 | ALDH1A1 (0.47) | LMNASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13819873 | 0.65 | ALDH1A1 (0.43) | LMNASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19825531 | 0.64 | ALDH1A1 (0.46) | LMNASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16951433 | 0.63 | CTSS (0.34) | SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103649056-B | Fused heterocyclic compounds as modulators of ion channels | GILEAD SCIENCES, INC. (US) | 2016-04-27 | — | — | CN | disclosed |