SCHEMBL2806249

SCHEMBL2806249

O=C(O)c1cnc(C(=O)O)c(C(=O)O)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
ALOX15 P16050 4/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 8/20 0.41
NAPRT Q6XQN6 2/20 0.41
HCAR2 Q8TDS4 2/20 0.41
TSHR P16473 3/20 0.41
ACMSD Q8TDX5 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
P4HTM Q9NXG6 3/20 0.40
P4HA1 P13674 1/20 0.40
MIF P14174 1/20 0.40
AKR1B1 P15121 1/20 0.40
HIF1A Q16665 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.37
LMNA P02545 1/20 0.37
ASPH Q12797 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27729620 0.87 ALDH1A1 (0.44) ALDH1A1ALOX15HPGDHSD17B10MAPT
SCHEMBL9401880 0.86 ALDH1A1 (0.43) ALDH1A1ALOX15HPGDHSD17B10MAPT
Hydrochloric Acid SCHEMBL9401842 0.84 ALDH1A1 (0.42) ALDH1A1ALOX15HPGDHSD17B10MAPT
SCHEMBL17501714 0.82 AKR1B1 (0.49) ALDH1A1ALOX15HPGDHSD17B10MAPT
SCHEMBL10335107 0.80 ALOX15 (0.46) ALDH1A1ALOX15HPGDHSD17B10MAPT
SCHEMBL27751225 0.80 ALDH1A1 (0.46) ALDH1A1ALOX15HPGDHSD17B10MAPT
SCHEMBL8036261 0.76 ALDH1A1 (0.43) ALDH1A1ALOX15HPGDHSD17B10MAPT
SCHEMBL29432473 0.74 ALDH1A1 (0.41) ALDH1A1HPGDMAPTSMN1; SMN2KDM4E
SCHEMBL29860451 0.74 PLAU (0.47) ALDH1A1ALOX15MAPTSMN1; SMN2KDM4E
SCHEMBL20046666 0.74 MEN1 (0.47) ALDH1A1ALOX15HSD17B10MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111760592-B Ion exchange resin-based composite material and preparation method thereof 南京工程学院 2022-06-07 CN claimed
CN-109320729-B Method for constructing metal manganese organic framework compound based on pyrazine polycarboxylic acid ligand and application 常州大学 2021-04-30 CN claimed
CN-111760592-A Ion exchange resin-based composite material and preparation method thereof 南京工程学院 2020-10-13 CN claimed
CN-109320729-A The method and application of manganese metal organic frame compound are constructed based on pyrazine polycarboxylic acid ligand 常州大学 2019-02-12 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
CN-102702239-A Transitional cadmium metal coordination compound with pyrazine tricarboxylic acid as organic ligand and preparation method of coordination compound UNIV TIANJIN POLYTECHNIC 2012-10-03 CN claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
JP-7097310-A None JP disclosed
US-20230076686-A1 LOW ODOR HIGH LEVEL DISINFECTANT MEDIVATORS INC. 2023-03-09 US disclosed
CN-112585228-B Polyimide varnish for coating conductor containing aromatic carboxylic acid and method for producing same PI尖端素材株式会社 2022-07-08 CN disclosed
CN-111760592-B Ion exchange resin-based composite material and preparation method thereof 南京工程学院 2022-06-07 CN disclosed
WO-2021141740-A1 LOW ODOR HIGH LEVEL DISINFECTANT MEDIVATORS INC. (US) 2021-07-15 WO disclosed
CN-109320729-B Method for constructing metal manganese organic framework compound based on pyrazine polycarboxylic acid ligand and application 常州大学 2021-04-30 CN disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
JP-H0797310-A SKIN-BEAUTIFYING COSMETIC SANKOUDOU:KK 1995-04-11 JP disclosed
EP-0194058-B1 PROCESS OF PREPARING POLYAMIDES AND/OR POLYIMIDES MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-11-08 EP disclosed
US-4795795-A Catalytic preparation of polyamide or polyamide-polymide with N,N'-dimethyl alkylene urea solvent MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-01-03 US disclosed
EP-0194058-A2 Process of preparing polyamides and/or polyimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-09-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 ALDH1A1 1901/4885ALOX15 914/4885HPGD 311/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB ALDH1A1 4765/4885ALOX15 608/4885HPGD 3660/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA ALDH1A1 1510/4885ALOX15 383/4885HPGD 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.