Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031466 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL28062590 | 0.77 | HSP90AA1 (0.39) | KDM4EALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL28062628 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL27528325 | 0.74 | ALOX15 (0.55) | KDM4EMAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL27891889 | 0.74 | CA2 (0.47) | KDM4EALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL27525744 | 0.73 | NLRP3 (0.59) | KDM4EALDH1A1MAPTKMT2AHDAC1 | |
| SCHEMBL28049897 | 0.73 | CASP3 (0.51) | KDM4EALDH1A1HSP90AA1SMN1; SMN2HSD17B10 | |
| SCHEMBL27382485 | 0.72 | DAO (0.51) | KDM4EALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL2601974 | 0.72 | INSR (0.54) | KDM4EALDH1A1MAPTKMT2AHDAC1 | |
| SCHEMBL28062629 | 0.72 | MTNR1A (0.46) | ALDH1A1MAPTMTNR1AMTNR1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102952062-B | Replace benzo-heterocycle compound and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2016-06-08 | — | — | CN | claimed |
| CN-102952062-B | Replace benzo-heterocycle compound and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2016-06-08 | — | — | CN | disclosed |