SCHEMBL28062799

SCHEMBL28062799

CCC(CC)O[SiH2]c1ccc(Cl)cc1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34
LMNA P02545 1/20 0.33
CYP2A6 P11509 1/20 0.33
AOC3 Q16853 1/20 0.33
SLC6A4 P31645 5/20 0.33
SLC6A3 Q01959 3/20 0.33
SLC6A2 P23975 4/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CYP2D6 P10635 2/20 0.31
NOS2 P35228 2/20 0.31
CRHR1 P34998 1/20 0.31
ADRB2 P07550 1/20 0.31
PDE7A Q13946 1/20 0.30
IDO1 P14902 1/20 0.30
AGXT P21549 1/20 0.30
KDM1A O60341 1/20 0.30
RCOR1 Q9UKL0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL710832 0.89
SCHEMBL712793 0.77 PRKCA (0.34)
SCHEMBL23493406 0.75 MAPT (0.35) HTTMEN1KMT2A
SCHEMBL31416082 0.74 LMNA (0.36) LMNACYP2A6AOC3SLC6A4SLC6A3
SCHEMBL28729098 0.73 LMNA (0.40) LMNACYP2A6SLC6A4ADRB2IDO1
SCHEMBL702168 0.72 LAP3 (0.33)
SCHEMBL19088418 0.70 L3MBTL1 (0.44) SLC6A4CYP2D6
SCHEMBL6708272 0.70 LMNA (0.32) LMNA
SCHEMBL10875297 0.69 L3MBTL1 (0.41) SLC6A4CYP2D6
SCHEMBL28523169 0.68 SLC6A3 (0.38) HTTLMNACYP2A6SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555901-A Polishing composition FUJIMI INC 2016-05-04 CN disclosed