Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064076 | 0.85 | PPARG (0.47) | PPARGPPARDPPARACHRM5HTR7 | |
| SCHEMBL28088135 | 0.84 | PPARG (0.40) | ALDH1A1KCNA5KDM4ESMN1; SMN2LMNA | |
| SCHEMBL28064163 | 0.83 | ALDH1A1 (0.38) | SIGMAR1ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL28064161 | 0.82 | HCRTR1 (0.42) | SIGMAR1ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL2228734 | 0.81 | GRIN2B (0.46) | ALDH1A1KMT2AGAAL3MBTL1KCNA5 | |
| SCHEMBL28064071 | 0.81 | ALDH1A1 (0.38) | SIGMAR1ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL28064074 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2AGAAL3MBTL1KCNA5 | |
| SCHEMBL28064061 | 0.81 | PPARG (0.37) | KCNA5PPARGPPARDPPARACHRM5 | |
| SCHEMBL28064167 | 0.80 | KCNA5 (0.46) | ALDH1A1KMT2AL3MBTL1KCNA5KDM4E | |
| SCHEMBL28064064 | 0.79 | TEAD1 (0.41) | ALDH1A1KMT2AGAAKCNA5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |