Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28088135 | 0.91 | PPARG (0.40) | PPARGPPARDPPARAGRM5F10 | |
| SCHEMBL28064161 | 0.86 | HCRTR1 (0.42) | PPARGPPARDPPARACHRM5 | |
| SCHEMBL28064164 | 0.85 | SIGMAR1 (0.38) | PPARGPPARDPPARAHTR7CHRM5 | |
| SCHEMBL28064061 | 0.85 | PPARG (0.37) | PPARGPPARDPPARAGRM5CHRM5 | |
| SCHEMBL28064203 | 0.83 | PPARG (0.46) | PPARGPPARDPPARAGRM5CYP1A2 | |
| SCHEMBL2228183 | 0.81 | GRM5 (0.46) | PPARGPPARDPPARAGRM5CYP1A2 | |
| SCHEMBL28064167 | 0.81 | KCNA5 (0.46) | PPARGPPARDPPARA | |
| SCHEMBL28064074 | 0.79 | ALDH1A1 (0.42) | — | |
| SCHEMBL28064063 | 0.79 | KDM4E (0.40) | TSHR | |
| SCHEMBL28064165 | 0.77 | CHEK2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |