Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064061 | 0.87 | PPARG (0.37) | CHEK2PPARGPPARDPPARACHRM5 | |
| SCHEMBL28064076 | 0.86 | PPARG (0.47) | PPARGPPARDPPARACHRM5 | |
| SCHEMBL28064074 | 0.85 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL28088135 | 0.84 | PPARG (0.40) | KDM4EALDH1A1SMN1; SMN2POLBPPARG | |
| SCHEMBL28064165 | 0.84 | CHEK2 (0.42) | CHEK2 | |
| SCHEMBL28064064 | 0.83 | TEAD1 (0.41) | KDM4EALDH1A1SMN1; SMN2HCRTR2PPARG | |
| SCHEMBL28064059 | 0.83 | HRH3 (0.39) | POLBHCRTR2HPGD | |
| SCHEMBL28064164 | 0.82 | SIGMAR1 (0.38) | KDM4EALDH1A1SMN1; SMN2SIGMAR1PPARG | |
| SCHEMBL2227918 | 0.81 | GRIN2B (0.44) | HCRTR1KDM4EALDH1A1CHEK2SMN1; SMN2 | |
| SCHEMBL28064167 | 0.79 | KCNA5 (0.46) | KDM4EALDH1A1SMN1; SMN2PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803258-B | Alkyl-heterocyclic carbamate derivatives, their preparation and therapeutic use | SAI NUOFEI (FR) | 2016-04-20 | — | — | CN | claimed |
| CN-105837565-A | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | 赛诺菲 | 2016-08-10 | — | — | CN | disclosed |